Glycosuria in Diphtheria

Physiological Disturbances during Experimental Diphtheritic Intoxication. Iii. Respiratory Quotients and Metabolic Rate.

Previous investigators have demonstrated disturbances of carbohydrate metabolism during both clinical and experimental diphtheritic intoxication. These disturbances are made manifest by delayed sugar tolerance curves, high blood sugar values, and, occasionally, glycosuria. These observations have led to the assumption on the part of many that, during the course of diphtheria, there exists a rel...

Tetanus and Diphtheria Seroprevalence in Patients Infected With Human Immunodeficiency Virus

Background and Objectives: HIV infected patients are at risk for vaccine-preventable infections such as tetanus and diphtheria (Td). In these patients, these antibodies tend to decline faster. Due to the limited data, this study assessed the seroprevalence of tetanus and diphtheria antibodies in HIV infected patients in Tehran, Iran. Materials and Methods: This case-control study was carried o...

Studies on Diphtheria- Tetanus, combined immunization in children in some elementary school of Teheran

Preparation and Evaluation of Diphtheria Toxoid-Containing Microspheres

Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children

Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured DTwP vaccine administered to preschool children in a number of health centers of Tehran in 2...